The study showed that the macrophages do die and release the ink they are holding, but your body interprets this as fresh ink. That means that new macrophages come to gobble it up, and the cycle continues. While this particular study utilized mice, the researchers suggest that a similar biological process is at play in humans, too. While sun damage is cited as one of the main reasons for tattoos fading, the researchers think that, over time, macrophages die off and are not replaced. In other words, the ink is dissolved in the human body. Interestingly, they’re using these findings to test a new method of removal—the extraction of macrophages. “Like all wounds to the skin, tattoos will heal better under greasy conditions,” said holistic dermatologist Cybele Fishman, M.D. She recommends using a greasy ointment like Vaniply, Waxelene, or Cerave Healing Ointment twice a day. Steer clear of Neosporin (also known as Neomycin), as Dr. Fishman pointed out it’s one of the top 10 contact allergens in the United States. Sarah Villafranco, M.D., skin care expert and founder of Osmia Organics, said, “Our lip repair is my favorite thing ever for tattoos! And straight up petroleum jelly is not a bad choice either, if you don’t mind using a petroleum-based product.” Dr. Fishman maintains that you should wash the area with fragrance-free soap and warm water daily, avoid picking, and protect the area well with sunscreen. “If you are having tenderness or there is pus in or around the tattoo, see a physician—you may need a topical antibiotic or an oral antibiotic if the infection is more severe,” she said. Thinking about getting more tattoos? First, find out which is safer: machine or handpoke?